Depends a lot on the length of your 5th wheel. Moving the pin box to the lowest setting (giving you the most bed rail clearance) would help. You should also have a good collection of boards on hand in case you need to reduce an angle at the top and/or bottom.
2021 Chevy Silverado LTZ 3500 Diesel
2022 Montana Legacy 3931FB
Pull-Rite Super Glide 4500