Once you get to your Tire Size and Load Range, the tires you choose from have the same what I'll call "stated capabilities." Specifically, they will all work off the same Load-to-Pressure Chart, and have the same maximum load/pressure ratings. Your 225/75R16 tires have to be "LT" for Light Truck (some car tires come out in the same size) and "LR" (Load Range) "E" because of the rear axle capacity of the E450 chassis. So you want LT225/75R16E labeling on new tires.
But all tires with that labeling are not created equal. In addition to tread style, there are different numbers of plies in tread and sidewall along with what they're made of. For example, in Michelin, the LTX series is not as ruggedly built as the RIB series. I didn't look at BFG, but I think their "Commercial" series probably has more plies from steel than "Long Trail" does, again in the same size and labeling.
Because you have a 24-ft coach, I doubt you will approach the max load ratings of the tires your chassis calls for. A 31-ft coach WILL max out the tires. For this reason, I think nearly any tire with the right labeling will serve you well. I'd be looking for a brand that'll offer replacements where you'll be operating. If you want to travel coast to coast, into AK and Lower 48, then find a brand with national presence. If you camp locally, not as critical.
OH LABELING! Tires carry a Date Code of Four Digits. First two are the Week within the Year, so it'll be somewhere 01-52. Last two are last two dates of Year, so 1214 would be very fresh tires, made "last month." Tires deteriorate on age, and in RV use we don't usually wear them out. So date is important.
If God's Your Co-Pilot Move Over, jd
2003 Jayco Escapade 31A on 2002 Ford E450 V10 4R100 218" WB