The good news is that unless totally abused the Allison 3000 and 4000 6 speed transmissions are close to bombproof.
Same for diesel engines during that time period. Sure, if run out of oil or WAY overheated, they can die prematurely.
And, yes a clogged CAC (Charge Air Cooler) which is immediately behind the fan on rear radiator coaches would suggest that it has not been maintained as it should and MAY have been overheated.
If you are novice at this, make any contract "Contingent upon inspection satisfactory to buyer". Hire an independent inspector who is both familiar with chassis and RV house systems. Yes, if you already know the RV house systems and can check them yourself, then the chassis part is all you need. Let's face it, you could replace every appliance in a motorhome and have money left over for the price of an engine, so the chassis/drivetrain is what you want closely inspected.
Is a good inspection a guarantee that there will be no problems-- I think all of us know that isn't true. But, it goes a long way, and if issues are found during an inspection, opens the door to renegotiate the price or if an inspection reveals excessive issues, to move on to the next coach.