Depends on the tire type and brand.
Carlisle says replace every 3-5 years and definitely after 5 years.
LT and P tire mfg has stated replace after 7 years.
Now having said that my '97 5er still has the orig ST225/75-15 D Carlisle as the spare. It hangs under the front between the landing gears.
I upgraded to 16" LT E tires many years ago and the ST spare has never sat on the ground.
"good judgment comes from experience, and a lot of that comes from bad judgment" ............ Will Rogers
'03 2500 QC Dodge/Cummins HO 3.73 6 speed manual Jacobs Westach
'97 Park Avanue 28' 5er 11200 two slides