All you can do is give it a try. We're traveling with two American Shorthairs. Like you, our two may very well out live me. Neither were ever outside cats and traveling they ride in a cage in the back seat area of our truck, would never leave them in the camper when traveling. One just lays down and passes out and hardly moves, the other rests, but never seems to close her eyes, they each have a bed and water, food, and litter box. Both have logged more miles than many people.
2018 Chevy 3500HD High Country Crew Cab DRW, D/A, 2016 Redwood 39MB, Dual AC, Fireplace, Sleep #Bed, Auto Sat Dish, Stack Washer/Dryer, Auto Level Sys, Disk Brakes, Onan Gen, 17.5" "H" tires, MORryde Pin & IS, Comfort Ride, Dual Awnings, Full Body Paint