I recently had knee surgery that has caused nothing but pain ever since. It has slowed me way down. I am in the (life long) process of remodeling my house. I am working on the family room now. I do everything with wood (and build and make my own stuff). I spend a LOT of time standing in my wood shop building stuff. With the pain in the leg, I have had to find alternative ways to do almost everything. Crawling, stooping, squatting, bending, lifting, carrying are excruciating difficult now. But I am determined NOTHING is going to stop me. I now work a little slower. I work a little more careful. I have to ask my wife to assist me a little more. I have to have my adult son carry lumber for me sometimes. But I still do it!
I told my wife recently, if I were paralyzed from my neck down ... I'd still find a way to run my radial arm saw! She laughed and said, "yes you would!"
Point being made ... when we experience physical limitations after a lifetime of health, if we are still determined ... we will find a way! It might be a little slower getting it done, but there is a way to do it!
If I were limited with only 1 hand, I'd make use of every device I have to hold, clamp, claw, grab, and secure and just go a little slower at it!