Unless you want to travel far out of the way your options are limited. Having driven that route for decades (Orange County to Modesto) here you go.99 south to where it meets I5.Whether you need it or not top off with fuel in Bakersfield and again in...
If you're in Washington during the summer months I recommend the Loop around the Olympic Peninsula in Northwest Washington. Allow lots of time to make many stops! If you're in decent shape take the walk to Neah bay. If the weather is good drive up...
Once you're done in the parks I'd head north to Lodi and cut across 12 (get gass)towards Fairfield. A little south and head up to Napa Valley for a day or two of wine tasting. Hotels are pricey but worth it. Drive up and down the valley wine tasti...
While 99 has improved a lot over the years the traffic has gotten worse with it. Lot of big rigs racing to wherever. I usually swing over to 101 for a much nicer drive and not as crazy much traffic. With a good GPS and some planning you'd be amaze...
On your way down I'd recommend an overnight in Ely NV for fuel and any stocking up you need to do. Check out the town, was pretty nice and friendly when I was last there. Heading down the east side of NV is a nice drive through differing eco system...