In November, you really should expect to hit snow....unless you plan to stay at Disney for over a month. Yes, there might be some light sleet in November, but normally no accumulating snow. If it starts to sleet and you feel that the road is possibly slick, stop and hang out for a bit at a rest stop and let VDOT work on the roadway. Then, take back off and head to your destination.
I-77 is the perfect road to be traveling in inclement weather because statistically over the years, it's been one of the most dangerous and they have installed lots of safety things and VDOT monitors it via video and weather information on a 24-hour basis.
I gave you a suggestion on another thread of Point South KOA in Yemassee, SC, which is just south of Walterboro. This would be about a 9:30 drive on the first day and a 4:30 drive on the second.
Have a great time, the weather should be about as close to perfect as you can get in Orlando.
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