We have taken 17 from Charleston, through Myrtle Beach and on up to Virginia Beach with a side trip to Nags Head and really enjoyed it. New Bern is a nice stopover if you have the time and enjoy Southern history(and the Birthplace of Pepsi).
2011 Excel 30RSO, 32', 3 slides, 4-Season 5th Wheel 2011 Ford F-250 XLT Super Duty, 6.2L V8, 385hp
If you have time, take the ferry route. It will take about 4 hrs between wait time and riding the ferry's , but it was relaxing and worth it, as long as the weather is good.