We took that road from West to East last fall when we were exploring that area towing a 28 ft 8k TT and I don't recall anything negative other than the price of diesel.
Should you be going between 101 and hwy 1 Manchester state park area do not even think about the mountain view rd. That one made for a white knuckle, way to big of rig and not nearly enough truck sort of day. 17 plus percent grade, with hitting the steering stops sort of switchbacks result in your having traction issues on dry pavement. On the downhill slopes zero to redline in first gear, even with the engine brake happened in about a tenth of a mile. It was very hard on the brakes.
2015 Ram 3500 Laramie CTD, 4X4, AISIN, B&W Companion Puck Mount
2016 Heartland Bighorn 3270RS, 1kw solar with Trimetric and dual SC2030, 600 watt and 2k inverters.