If you take 395, 36 and 44 to Old Station, the remainder of the trip is about the same time whether you get to the coast and head up, or if you take 89, I-5, 199. If weather is not a factor, but driving fatigue could be, I would get to Grants Pass and come down 199.
what coolbreezeo1 said. We took that route in reverse and it was a good trip. 299 is twisty and a bit hilly but just allow plenty of time to go slow and enjoy the view!! We have a 34' DP and toad.
Lonny & Diane 2004 Country Coach Allure 33' "Big Blue" Towing 2008 Chev Colorado 4x4 Semper Fi