We have been over Tioga Pass many times, we live just 65 miles east of Reno and prefer the Tioga Pass route into Yosemite over taking I-80. The only problem you might have with the motorhome is the engine/tranny may get a little warm, just pull over and let it cool down if that happens. There are plenty of places to pull over on your way up to the Park entrance. There is a Quick Stop type Mobile Gas Station on the left just as you turn off US395 onto SR120 going up the mountain named the Whoa Nellie Deli that has really great Fish Tacos and other foods you would not expect in a place like that. They have a full menu and it's worth the stop, plenty of parking for the motorhome also.
Bill
2013 Arctic Fox 27-5L, B&W Hitch, Twin Honda EU2000i Generators, Tri Metric Battery Monitor, Reese 5th. Airborne.
โGoing to the mountains is going home.โ John Muir