We did our traveling all over the US and Canada in a PW Excel, a true Class B and recently sold it and replaced it with a Pursuit. The Excel was definitely better for mobility and parking. We visited many cities and towns while we had it, as well as national and state parks. We always slept at nite in campgrounds and ran around in it during the day, it was great fun. Because of the limited bathroom, we normally used campground showers and every week to 10 days got a motel room for a nite or 2 or stayed in a commercial RV park where we knew the shower facilities were good (sometimes they aren't).
Our new Pursuit is working out very well. We have no need to stay in a motel or commercial RV park any more, preferring state and federal campgrounds. When we need to wash clothes, instead of using the expensive and usually second rate laundry rooms at an RV park, we pull into a small town and find a big washateria and get the laundry done faster. We also wanted the overhead bunk for our granddaughter. The Pursuit is easy to drive, actually better than our Excel, but not as easy to park.
Your comment about pulling into a campground every few days to empty the tanks is not clear to me. Do you intend to just park somewhere in a lot or on the street? That doesn't sound very appealing to me and I don't think it is a good idea. There are public and private campgrounds near any place you want to go, including New York, Washington DC, Toronto, etc., or you can stay in a hotel if absolutely necessary (I realize your bride doesn't like hotels) You will need an electrical hookup anywhere you need AC to sleep or run a generator all night, also not very appealing to me, so a campground is a lot better. Best of luck with your new adventure, traveling around the US and Canada can't be beat for a good time.