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Valley fever treatment trials

RVUSA
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By Paige St. John
September 24, 2013, 8:00 a.m.



BAKERSFIELD -- Federal health officials have announced they are planning clinical trials of two common treatments for valley fever.


U.S. Rep. Kevin McCarthy, who has worked for several years to increase federal response to valley fever, says the clinical trials will raise awareness of the fungal disease and inch it closer to being combated with a vaccine. "That is our ultimate goal," he told a packed meeting hall of valley fever victims and survivors Monday evening in Bakersfield.

The study is being planned jointly by the Centers for Disease Control and the National Institutes for Health. The agencies hope to recruit local physicians to enroll patients who have symptoms of valley fever-related pneumonia. Half would immediately begin receiving a combination of drugs that include fluconazole, an anti-fungal medication. The other half would receive only a drug used for bacterial pneumonia.

The goal of the clinical trial is to determine if early treatment by the most commonly used anti-fungal drug makes a difference. However, NIH director Dr. Francis Collins warned those attending the crowded public forum during a research symposium on the disease that it would probably take a year before patients are actually recruited for the study, and four to five years more to learn the results.

Valley fever, the local term for coccidioidomycosis, is caused by spores of a fungus that lives in the soils common to California's Central Valley. Experts at the symposium said about 40% of the population in Kern County has contracted the fungus at some point, and 40% of those individuals develop symptoms that range from fever and weakness to pneumonia, meningitis and fungal growths that spread throughout their body.

Collins and other medical experts stress there is no known cure. Most individuals develop immunity to the fungus, but for others, it remains in the body. Current treatment consists of a lifelong regimen of drugs to prevent the fungus from spreading.

-- The article included a picture of a solar panel farm and a caption that talked about an outbreak of the disease in the county of that farm. moral: don't snowbird near the solar farms.
4 REPLIES 4

WyoTraveler
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beliveauj wrote:
A few years back my wife got it on our way back to Mn.from Az.As we live a few miles from Rochester,Mn.we went to the Mayo Clinic where they did some tests and came out to tell us that she had a mass on her lung and that the cancer was in the advanced stages and treatment wouldn't help.(What a blow that was)I emailed our friend in AZ.and told them and they said "Have them check her for VF" which we had never heard of.She didn't have to take any drugs and she is doing great.


We also have a friend in WY that was diagnosed with lung cancer and they wanted to remove a lung. Fortunately he got a second opinion and found out it was VF not cancer.

beliveauj
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A few years back my wife got it on our way back to Mn.from Az.As we live a few miles from Rochester,Mn.we went to the Mayo Clinic where they did some tests and came out to tell us that she had a mass on her lung and that the cancer was in the advanced stages and treatment wouldn't help.(What a blow that was)I emailed our friend in AZ.and told them and they said "Have them check her for VF" which we had never heard of.She didn't have to take any drugs and she is doing great.
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WyoTraveler
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The big problem is snow birds getting VF and going back north where DRs have no idea what it is. Wife and I both got a mild case in AZ last winter. DRs in WY didn't have any idea about treatment. At least now our drs have been informed. My dr said if I come back north again with problem he will send me directly to pulmonary specialist. Last year I just recived steroids which covered and compounded the problem. We were just lucky it wasn't worse.

EPenney
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Thanks for the info. I'll share it with me fellow VF sufferers on the Valleyfeversurvivor.com forum. I've had a serious case of deciminated VF for 5 years, and was just taken off the Fluconazole 4 months ago on a trial basis to see if my immune system can fight the disease on it's own. So far so good. The side affects of Fluconazole are horrific. I was taking 800MG a day, and would do it again if necessary to stay alive.
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