While the coin toss may be as good as any, we frequently just roll through Cinci on I-75. When there was no construction (and I have not checked recently), it was no worse than any other interstate.
However, the I-275 south idea has a lot of charm. I have never driven that road, but just being outside of the city and getting to Kentucky sooner cannot be bad.
If it were actually my call, I would check with both AAA and Google for the latest conditions.
Matt
Matt & Mary Colie
A sailor, his bride and their black dogs (one dear dog is waiting for us at the bridge) going to see some dry places that have Geocaches in a coach made the year we married.