Where exactly are you going? Exit 432 (Rt. 411) puts you east of Sevierville yet and Wears Valley is west of rt.66 (Winfield Dunn pkwy). Yes, exit 432 is the most direct and it is good road that will handle a 33 footer just fine where Rt. 66 can be backed up with very heavy traffic depending on the day of the week and time of day too, so that 7 minutes could turn into a whole lot longer, or you could just sail through too, you just never know. Both are good roads.
As a local here and upon thinking which one I would take I would suggest 411. It will take you right by Bush Beans factory and museum/cafe which is worth the stop for a bite to eat and a quick walk through the museum, its not that big and its free.
Either way you go you will be fine really, just depends on what you want to do. Its busy around here right now with the leaf lookers so traffic is the big question.