I'm sure there are videos of the road as well as Google Streetview. It's been a while since I drove it (in a cuteute), but I don't recall anything particularly nasty about it. There are 'switchbacks' but they don't require 3 point turns (at least not for cars). Ultimately you have to judge whether your truck and trailer can handle the grade, some gravel, and the turns.
There was a recent thread about a washout that threatened and closed a bridge on UT 95 between the 261 turn off and Blanding. Google maps traffic says that stretch is closed until Oct 29.
Reviewing streetview, it looks like the topmost hairpin is the tightest, the one labeled as 'view of the valley of the gods'. I imagine a 18 wheeler would require skill, but a competent RV owner can handle it as well as most suburban street or cul de sac turns.
https://www.blm.gov/sites/blm.gov/files/documents/files/Utah_BENM_Valley-Of_Gods_Brochure.pdfhttps://vanlifewanderer.com/2021/06/12/is-moki-dugway-safe/