I haul my VTX1800T (~800lbs) slightly to the right of center. This places it evenly between the floor rings that are shifted to the right because of the kitchen; I have a shorter trailer. I do not have any issue with the trailer being loaded unevenly side-side.
I also do not use a wheel chock. I place the front of the front tire between the two rings then take a strap with one complete wrap around the tire and cinch it down to keep the bars from turning left or right. Then have a strap on each side pulling forward from the bars to the same rings to slightly compress the forks. Two straps pulling on frame backward to keep bike from sliding forward. Then one strap with one full wrap on rear tire to nearest rings to keep back of bike from bouncing/sliding to the side. It takes a little longer (and 6 straps) to secure the bike but I have no issues with anything sticking up to stub a toe on for a wheel chock, but there are many options to secure a chock.
Thousands of miles without issue.
2005 2500 Cummins/48RE/3.73, QCLB, 4wd, BigHorn, Edge Juice w/ CTS + Turbo Timer,Transgo Shift Kit ISSPro Oil and LP pressure gauges, GDP 20/2 filters, Custom Diesel Steering Box Brace
'10 Forest River Shockwave Toy Hauler 21'
Honda EU3000I Genny