John, it depends on what kind of rig you have. I looked up your stats and could not tell if you even have a TC. If you do, and have 4WD, the route through Tehachapi is probably still the best coming from the south through Trona and the Panamint Valley. We live on the west slope/Sierra Nevada and drive through Reno and take 395 south, cutting over to enter DVNP from the north at Big Pine. Lots of washboard on the 50 miles of sandy roads, but little used without the terrible grades you encounter going over the Panamints: (endless miles of auto transmission withering; brake burning, 6-8% grades). There were some big washouts this fall in the park (I'm so sorry I missed that) so you need to visit their website to see what is open and what is not.
My fave website for the Desert Areas of the southwest is: DesertUSA. Up to date reports and pix will whet your appetite. I'm thinking this will be a great year for wild flowers in DV. DesertUSA will let you know. Since the server kept dropping this post, I went to DVUSA and the reports confirm the wildflower bloom is underway.
jefe
'01.5 Dodge 2500 4x4, CTD, Qcab, SB, NV5600, 241HD, 4.10's, Dana 70/TruTrac; Dana 80/ TruTrac, Spintec hub conversion, H.D. susp, 315/75R16's on 7.5" and 10" wide steel wheels, Vulcan big line, Warn M15K winch '98 Lance Lite 165s, 8' 6" X-cab, 200w Solar