Once you hit the middle of Kentucky and Soutward, you'll find almost every campground open for business with their available hook-ups. We travel South in December and again in March, I-75 all the way through Atlanta Georgia, or I-75 to Knoxville, TN, then I-40, then I-26 and Southward through South Carolina. Never had any problems just randomly finding a campsite. All your KOA's will be open with full hook-ups. State Parks are still open too. So, pick your destination and just see what's in the area. Call, make sure they have space available (and are truly open), and then just go!
FYI, Indiana got hit with the ice. It started where I live about 4:00 am, and by 7 am, the snow started. It's truly a treacherous mess right now on the roads. Drive careful and get out of Ohio.... very soon. It's coming your way!