The main things to consider are:
1. If you will do a LOT of driving with said rig and put many, many miles on it, the oil burner is the ticket. It takes a long time and many miles to recoup the up to $10K cost of a diesel engine. If only moderate miles, the V10 gets the nod, in my book.
2. If you plan to do a LOT of hilly, mountainous miles, or at high altitude with a heavy payload or tow, the oil burner wins again. If only moderate exposure to ups and downs, the V10 gasser wins the toss.
3. Diesels retain a lot of their value for a long time. This makes them expensive in the used market, especially the Dodge/Cummins which has a near cult following. Gas engines depreciate faster. So, if buying used, a low mileage gasser would be a better bet, especially if you don't drive massive amounts of miles.
4. The reason I bought a Dodge/HO Cummins new in 2001 is I thought it wise to buy a drivetrain that would outlive me. So far, so good. Simply trouble free. Oh, and the NV5600, NV241HD t. case (with the extra wide chain) and the first year of the Dana 80/35 spline rr diff with Power Lok, and the first year of big disc brakes all around. These are a few of my favorite things.
jefe
'01.5 Dodge 2500 4x4, CTD, Qcab, SB, NV5600, 241HD, 4.10's, Dana 70/TruTrac; Dana 80/ TruTrac, Spintec hub conversion, H.D. susp, 315/75R16's on 7.5" and 10" wide steel wheels, Vulcan big line, Warn M15K winch '98 Lance Lite 165s, 8' 6" X-cab, 200w Solar