Is the F450 Chassis or Pickup type? Also, are your overloads engaged and are you running air bags? What year is the truck?
If you are running air bags either add extended bump stops or lower the air to engage the overloads. If you are getting upper stable loads that should engage the overloads. If this is an older F450, you should also upgrading to Bilstein 4600s or similar. They made an amazing differencing in the ride of my F450.
Finally, check the tire pressure in all of the tires.
'10 Ford F-450, 6.4, 4.30, 4x4, 14,500 GVWR, '06 Host Rainer 950 DS, Torklift Talon tiedowns, Glow Steps, and Fastguns. Bilstein 4600s, Firestone Bags, Toyo M655 Gs, Curt front hitch, Energy Suspension bump stops.
NRA Life Member, CCA Life Member