Bcam,
There sure is a lot to see everywhere. I don't know what your interests are, but if you are way close to the bottom of the lakes, plan two days is Chicago (parking is bad and expensive), for the Shedd Aquarium, the Field Museum and the (of course) the Museum of Science and Industry. Now, this will take a little doing, there is a wonderful car museum called the Gilmore in Hickory Corner MI and that is not that far off the highway between Kalamazoo and Battle Creek. There is the Air Zoo in Ka'zoo. It got called that because they house a collection of privately owned Grumman Cats. Then you have to make a decision to go south to the Cord-Auburn-Duesenburg and National Truck Museum (two that are close together) or north to the Detroit museums of Henry Ford and GreenField Village. Unfortunately, both that complex and the Airforce Museum at Dayton are both what I call one day museums. By that I don't mean they will take a day, both will, but if you are within a day's drive, you should not miss either and they are most of a day apart....
The Rock and Roll Hall of Fame in Cleveland is about a half hour museum by the about account. If you get near Erie PA, there is an neat (small but neat) museum all about the naval actions on Lake Erie during the War of 1812.
Upper New York (don't have any loaded weapons) is just amazing scenery. If you get near Johnstown, the flood museum is a nice, but a short stop.
As others have said, stay away form New York City. If you are going East of there, cross the Hudson at the Tappen Zee (Nyack and Terrytown) and plan east from there. I could write all night about New England, I love it and I wish I lived there still.
Lets turn you south to the DC area. Pass up Philadelphia unless you have a native guide. The Liberty Bell is best read about and everything else is buildings. it is a typical megapolis east coast city.
The National Aquarium is in Baltimore, but I have only ever been there by passcar. It is very good and very large.
On to the Smithsonian(s)... You do that it is about seven major and a bunch more smaller museums - Right? The Air and Space can kill a day. Last time we were there, we only had three days and even though it was a second visit for DW and Yours Truly, the kids felt cheated and they were right.
You can see most of what matters about DC just driving though it (again a megapolis just be patient). You might want to park and walk the Lincoln and a couple of other memorials.
There is history all over the east, but I will only direct you to two more. The first is the Mariner's Museum in Newport News. This is where the Monitor is being recovered. It is guaranteed to surprise you. That was much more a ship than you might have ever expected.
If you drive the Outer Banks to get to Hatteras most of it is tourist trap, but the real museums (Wright Bros., Hatteras and others) are pretty good, but watch the prices. The ferry to Cedar Island is a great boat ride. You can overnight in their lot.
About another couple of days (or so) south of there is Charleston. An interesting place on its own, But do not miss the Hunley. It isn't a cheap show, but it is well worth it.
Savannah is a beautiful city and much too tight for most RVs in the historic district.
My fingers are tired now, so I will leave you to continue planning on your own.
Matt
Matt & Mary Colie
A sailor, his bride and their black dogs (one dear dog is waiting for us at the bridge) going to see some dry places that have Geocaches in a coach made the year we married.